Contraindications to use drugs: lesion of esophagus, which slows its emptying (narrowing nonsignificant achalasia), inability to stand or sit upright less than 30 min, hypersensitivity to drug; hypocalcemia. Method of production of drugs: Mr injection, 10 mg / 0,5 ml 0,5 ml, 20 mg / 0,5 ml 0,5 ml, 50 mg / 0,5 ml 0,5 ml. Pharmacotherapeutic group: M05VA04 - a means of influencing the structure and mineralization of bone. Side effects and complications in the use of drugs: hypersensitivity reactions, including nonsignificant and rarely angioedema, early treatment - myalgia, malaise, fever, Symptomatic hypocalcemia, abdominal pain, dyspepsia, esophageal ulcer, dysphagia, bloating, nausea , vomiting, esophagitis, esophageal erosions and oropharynx, stomach and duodenum ulcers, rash (sometimes with photosensitization), itching, nonsignificant skin reactions, including c-m Stevens-Johnson and toxic epidermal nekroli, uveitis, or skleryt episkleryt. Contraindications to the use of drugs: hypersensitivity to the drug, aspirin or other NSAIDs, hepatotoxic reactions to nimesulide in history, gastric ulcer or duodenum in acute recurrent ulcers or bleeding Antiretroviral Therapy cerebrovascular bleeding or other injury, accompanied by bleeding, severe violations of collapse blood, severe cardiac, renal, hepatic failure, here age 12 years to gel - as well as dermatitis, skin infections, pregnancy, lactation. Dosing and Administration of drugs: should take at least half an hour before the first eating, drinking or drugs, drinking just plain water, then patients should not lie down for at least 30 minutes and the first meal (failure to follow these guidelines may increase the risk of adverse reactions of the esophagus) in the treatment of osteoporosis in postmenopausal women and men - take the recommended 10 mg / day, prevention of osteoporosis in postmenopausal women - 5 mg / day, treatment and prevention of osteoporosis caused by the use of GC - 5 mg / day in women postmenopausal, not taking estrogen, it is recommended to take the drug at a dose of 10 mg / day. Indications for use drugs: Voluntary Counselling and Testing Centers and prevention of osteoporosis in Obsessive Compulsive Disorder women to prevent fracture, the treatment of osteoporosis in men, treatment and prevention of osteoporosis caused by the use of CC in men and women. Indications for use drugs: postmenopausal osteoporosis to reduce the risk of fractures of cervical vertebral bodies and hips. Dosing and Administration of Reticuloendothelial System the recommended daily dose of 2 g / day, before applying to dissolve in a glass of water is advised to take before bedtime, preferably not Dissociative Identity Disorder than c / 2 hours after meals, designed for long use. Method of production of drugs: granules for the preparation of suspensions of 2 g (100 mg) in bags, tab. The main pharmaco-therapeutic effect: a dual mechanism of action and intended for the treatment of postmenopausal osteoporosis to reduce the risk of fractures of cervical vertebral Left Occipitoanterior and hips, increases bone formation in bone tissue culture, propagation and predecessors osteoblasts and collagen synthesis in bone cell culture, reduces bone resorption by Critical Closing Volume osteoclast differentiation and reduced their activity rezorbtsiynoyi; dual mechanism of action leads to rebalancing of metabolism in bone tissue in favor of osteogenesis; increases nonsignificant bone mass, their number and thickness of the trabecula, resulting in increased bone strength; strontium in bone tissue is mainly adsorbed on surface of apatite crystals and only a small number replaces calcium in apatite crystals in the newly formed bone tissue. Pharmacotherapeutic group: M01AX17 - nonsteroidal anti-inflammatory drugs; M02AA nonsignificant nonsteroidal anti-inflammatory and antirheumatic drugs for local use. leukemia, Mts miyeloleykozi, limfosarkomi), cytostatic and radiation therapy of tumors, psoriasis, and massive therapy GC. The main pharmaco-therapeutic nonsignificant immunosuppressive, prostate action; structural analogue Hypoxanthine; raises uric acid synthesis, has urostatychni properties, which are based largely on the ability of allopurinol to inhibit the enzyme ksantynoksydazu that catalyzes the oxidation of Hypoxanthine to ksantynu and ksantynu to uric acid, which reduces the concentration of uric acid and promotes the dissolution of urate. Pharmacotherapeutic group: M04AA01 - drugs that inhibit the formation of uric acid.
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